Die Dresdner Kanne om 47,1634 Fr.kt. är den under Art . Sachsen redan anförda . 1 Fuder = 12 Eimer 308,863 1 = 5,720 jumfr . Franskt vin , 1 Oxhoft 3 Eimer 

KT5720, protein kinase A inhibitor (ab141818)

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1 KT5720 was used to examine the role of PKA in various cellular events such as cell adhesion, 2 neurite MW 537.61, Purity > 98%. Potent, selective protein kinase A (Ki = 60 nM) inhibitor. Reversibly arrests human skin fibroblasts in the G1 phase. Cell permeable. KT-5720 is prepared by a modificiation of K-252a (sc-200517), which is synthesized by the fungus Nocardiopsis sp. KT-5720 is a potent, specific and cell-permeable inhibitor of PKA (Ki = 60 nM). This compound blocks PKA signaling through competitive inhibition.

KT 5720 is a potent allosteric modulator of this receptor; at concentrations as low as 10 nM, KT 5720 increases the affinity of acetyl-choline for M1 receptors by 40% (24). This suggests that KT 5720 may be inappropriate for studies in the nervous system or in neu-ronal cells expressing this receptor. These studies indicate that KT 5720 has

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